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Italian study reveals why some people are weaker in the face of Covid-19

2023-09-15 08:22:02Kosova&Bota SHKRUAR NGA REDAKSIA VOX

Italian study reveals why some people are weaker in the face of Covid-19

Genes inherited from the ancestor of Neanderthal man played an important role in the causes of mortality from Covid-19. A study by the Mario Negri Institute in Italy sheds light on the causes of the high mortality rate recorded in some areas, giving a decisive weight to the genetic predisposition of the population.

From the study published in the journal iScience, it can be seen that a certain region of the human genome was significantly associated with the risk of becoming seriously ill with Covid in the residents of the areas of Bergamo most affected by the pandemic during the first wave.

"The surprising thing is that 3 of the 6 genes associated with this risk came to the modern population from Neanderthals, specifically from the Vindija genome dating back 50,000 years. Once it probably protected Neanderthals from infections, now it causes an excess of immune response which not only does not protect us but exposes us to a more serious disease" explained Giuseppe Remuzzi, director of the Institute.

The victims of the Neanderthal chromosome in the world, he added, "are perhaps a million and may be precisely those who, in the absence of other causes, die from a genetic predisposition."

9,733 people from Bergamo and its province participated in the study and completed a questionnaire. "The results of the research give an answer to one of the questions that each of us has asked ourselves: why do some contract the virus asymptomatically and others in a serious form?" said the president of the Lombardy region.

This is an important step in the scientific knowledge of the SarsCoV2 virus, which comes as we prepare for the new vaccination campaign.


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