The U.S. Agency for International Development (USAID) headquarters in Washington was unexpectedly closed on Monday, and employees were notified by email after midnight not to come to work.
According to CNN sources, staff were told to work remotely, except for those performing essential functions in the building.
The closure comes amid efforts by President Donald Trump and Elon Musk to reform the federal government. Trump and his allies have criticized USAID as biased and favoring Democrats.
Technology entrepreneur Elon Musk stated via X that Trump agrees that the agency should be "shut down" after days of speculation about its future.
Musk claimed he had contacted Trump "several times" and he confirmed he would shut down the agency, which distributes billions in humanitarian aid and development funds each year.
On Sunday night, Trump said that USAID was run by "crazy radicals" and that he was removing them to decide the agency's future.
Meanwhile, two USAID security officials were administratively suspended after refusing to grant access to agency systems to members of the Department of Government Efficiency (DOGE). After several attempts, they managed to gain entry to USAID headquarters and, according to a post on X by a Trump-appointed official, the classified materials were only accessed by people with security clearance.