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Researchers cast doubt on the effectiveness of anti-wrinkle products

2026-06-27 17:14:30Lifestyle SHKRUAR NGA REDAKSIA VOX
Researchers cast doubt on the effectiveness of anti-wrinkle products
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A team of researchers from the Medical University of Graz, Austria, has published a scientific review on the role of the NAD+ molecule in aging and its therapeutic potential, according to "Science".

The study authors are Subhash Khatri, Mahmoud Abdellatif and Simon Sedej, who work in research departments related to cardiology, metabolism and the biology of aging, in Graz, Austria, and partner institutions in Europe. 

In the study published in the journal Geromedicine, scientists analyze existing clinical evidence on NAD+, an essential molecule for cellular metabolism, which is linked to energy production, DNA repair, and mitochondrial function.

Anti-aging products remain unproven, as there is still no clear evidence that they slow down aging in humans.

"Anti-aging" products sound futuristic, but science is still catching up to these claims.

Some of the most popular products claim to increase NAD+, a molecule involved in energy metabolism, DNA repair, inflammation, and cellular responses to stress.

NAD+ levels can decrease with age, which is why compounds like NMN and NR are marketed as “longevity” products.

There is a biological basis for this idea.

Human studies show that some NAD+ precursors can increase NAD+ or related biological markers in the blood.

But growing a molecule is not the same as experiencing a longer life, clearer thinking, stronger muscles, or slowing down aging.

Most human studies are still short-term and focused on biomarkers, not outcomes that people can actually feel.

Resveratrol (a natural plant compound found in some foods and plants, and belonging to the group of polyphenols – antioxidants), has a similar problem.

It shows promise in cells and animals, but the evidence in humans for anti-aging benefits is inconsistent across studies.

For now, the strongest evidence for healthy aging continues to point toward exercise, sleep, good nutrition, not smoking, limiting alcohol, and managing long-term health risks.


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