Tinnitus is a lifelong problem that can affect the entire population.
The perception of hearing a sound that is not actually present is a very common occurrence and everyone has experienced this phenomenon at least once.
About 750 million people suffer from it worldwide.
"But beware of neurodegenerative diseases that have whistling in the ears as a symptom," says Arianna di Stadio, professor of Otorhinolaryngology at the University of Catania and honorary researcher at "Queen Square Neurology" in London, on the occasion of World Ear Day.
"The perception of sounds and voice is a complex process that begins in the ear. After the ear cells are stimulated by a sound, such as that of a horn, they move, generating a nerve impulse that reaches the brain, where the horn is. In the case of tinnitus, the external auditory stimulus is absent and the cells move on their own, generating these phantom sounds," explains Di Stadio.
"This unstimulated motility is indicative of cell distress and can occur after an acoustic trauma, however this phenomenon is transient as the cells either recover their well-being or die and the ringing disappears," she adds.
"It is different when the tinnitus is continuous. This insistence is caused by the inflammation of the hearing area in the brain, after the peripheral stimulus coming from the ear. If the ear cells die they can no longer send signals, so the tinnitus should go away. In some people, however, this excessive stimulation can cause inflammation of a specific area in the brain, which remains active even in the absence of stimulation from the ear," Di Stadio points out.
"Some diseases, like multiple sclerosis, can cause tinnitus as a symptom, and we need to address the problem using methodologies capable of combating neuro-inflammation," she says.
"Currently, we are studying a series of anti-neuroinflammatory molecules to treat patients with tinnitus over six months. We have to prevent the disorder from becoming chronic", concludes Di Stadio.