It was considered a breakthrough in medicine. And in fact everything went well for about two months. But suddenly the patient died.
David Bennett, 57, died on March 8, shortly after becoming the first person in history to undergo an organ transplant from another species. Bennett, who was diagnosed with heart disease, had previously undergone groundbreaking experimental surgery in January. Doctors replaced his heart with a genetically modified pig one by one, modifying the animal to remove genes that could cause rapid organ rejection and replacing them with human genes that would help the body accept the new heart. .
The surgery seemed to be a huge success at first as his young heart was pumping fantastically a few days before his death. But about 40 days after the operation took place, Bennett's condition began to deteriorate rapidly and just a few days later, he died suddenly for no apparent reason, leaving his family and doctors saddened by what happened.
A new report from the MIT Technology Review, published May 4, found that Bennett's new heart may have been infected with a swine virus called 'swine cytomegalovirus', a preventable infection that could lead to side effects. destructive on the transplant recipient.
If true, the presence of swine cytomegalovirus represents a major unforeseen error on the part of scientists, given that donor pigs were supposed to grow in a specially monitored environment free of disease.
Yet, although tragic, the discovery of the swine virus in Mr. Bennett's heart is not necessarily bad news for the transplant. If a swine virus played a role in its death, it could mean that a virus-free heart xenotransplant could last much longer. Some surgeons believe that the last genetically modified organs could theoretically continue to work for years, and more rigorous procedures should be able to examine the virus in future cases.